• 林秋宁

    长聘教轨副教授,博士生导师,国家自然科学基金优秀青年基金获得者。

    2007获得华东理工大学学士学位,2013年获华东理工大学博士学位,同年留校从事博士后研究工作。2016-2017年赴美国华盛顿州立大学访问一年,20178月回国任华东理工大学副研究员,2020年初加入js345线路检测。2020年获中国生物医学工程学会青年学者奖,并获国家自然科学基金优秀青年科学基金资助。一直从事生物医用材料的基础和应用研究,创新性提出光化学偶联反应构建水凝胶的新方法和近红外光控制药物释放的新手段。在Adv. Mater.J. Am. Chem. Soc.Angew. Chem.等国际重要学术期刊上发表论文45篇,研究工作获得哈佛医学院、麻省理工学院、美国NIH等生物材料及医学领域相关知名研究组的高度评价。申/获中国及国际PCT专利10余项,授权6项,所建立的方法在生物医药领域具有重要的临床转化价值,已实现1项技术转化。主持国家自然科学基金、上海市人才计划等十余项项目。

研究方向

1)水凝胶生物材料

2)光智能生物材料

3)生物3D制造

4)药物控释

代表性论文专著

1.       M.-L. Dai#, B.-Y. Sui#, Y.-J. Hua, Y.-Q. Zhang, B.-K. Bao, Q.-N. Lin*, X. Liu*, L.-Y. Zhu, J. Sun*, A well defect-suitable and high-strength biomimetic squid type II gelatin hydrogel promoted in situ costal cartilage regeneration via dynamic immunomodulation and direct induction manners, Biomaterials, 2020, 240: 119841.

2.       Y.-J. Hua#, Y. Gan#, Y.-Q. Zhang, B. Ouyang, B. Tu, C.-M. Zhang, X.-P. Zhong, C.-Y Bao, Y. Yang, Q.-N. Lin*, Q. Zhou, L.-Y. Zhu, Adaptable to Mechanically Stable Hydrogels Based on the Dynamic Covalent Cross-Linking of Thiol-Aldehyde Addition, ACS Macro Lett., 2019, 8, 310-314.

3.       Q.-N. Lin#, L.-P. Yang#, Z.-Q. Wang, Y.-J. Hua, D.-S. Zhang, B.-K. Bao, C.-Y. Bao, X.-Q. Gong, L.-Y. Zhu*, Coumarin Photocages Modified with an Electron-Rich Styryl Moiety at the 3-Position: Long Wavelength Excitation, Rapid Photolysis and Photobleaching, Angew. Chem. Int. Ed., 2018, 57, 3722-3726.

4.       X.-L. Liu#, Y.-L. Yang#, Y. Li, X. Niu, B.-Z. Zhao, Y. Wang*, C.-Y. Bao, Z.-P. Xie, Q.-N. Lin*, L.-Y. Zhu, Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regeneration, Nanoscale, 2017, 9, 4430-4438.

5.       Y.-L. Yang#, X.-L. Liu#, Y. Li, Y. Wang*, C.-Y. Bao, Y.-F. Chen, Q.-N. Lin*, L. Zhu, A postoperative anti-adhesion barrier based on photoinduced imine-crosslinking hydrogel with tissue-adhesive ability, Acta Biomaterialia, 2017, 62, 199-209.

6.       Y.-L. Yang#, J.-Y. Zhang#, Z.-Z. Liu, Q.-N. Lin*, X.-L. Liu, C.-Y. Bao, Y. Wang*, L.-Y. Zhu*, Tissue-Integratable and Biocompatible Photogelation by the Imine Crosslinking Reaction, Adv. Mater., 2016, 28, 2724-2730.

7.       Z.-Z. Liu, T. Liu, Q.-N. Lin*, C.-Y. Bao, L.-Y. Zhu*, Sequential Control over Thiol Click Chemistry by a Reversibly Photoactivated Thiol Mechanism of Spirothiopyran, Angew. Chem. Int. Ed., 2015, 54, 174-178.

8.       Q.-N. Lin, C.-Y. Bao, Y.-L. Yang, Q.-N. Liang, D.-S. Zhang, S.-Y. Cheng, L.-Y. Zhu*, Highly Discriminating Photorelease of Anticancer Drugs Based on Tumor-Hypoxia Activatable Phototriggers Conjugated Chitosan Nanoparticles, Adv. Mater., 2013, 25, 1981-1986. (ESI高被引)

9.       Q.-N. Lin, C.-Y. Bao, S.-Y. Cheng, Y.-L. Yang, W. Ji, L.-Y. Zhu*, Target-Activated Coumarin Phototriggers Specifically Switch on Fluorescence and Photocleavage upon Bonding to Thiol-Bearing Protein, J. Am. Chem. Soc., 2012, 134, 5052-5055.

10.    Q.-N. Lin, Q. Huang, C.-Y. Li, C.-Y. Bao*, Z.-Z. Liu, F.-Y. Li, L.-Y. Zhu*, Anticancer Drug Release from a Mesoporous Silica Based Nanophotocage Regulated by Either a One- or Two-Photon Process, J. Am. Chem. Soc., 2010, 132, 10645-10647. (ESI高被引)

联系方式

邮箱地址:qiuninglin@sjtu.edu.cn

办公地址:闵行校区文选医学楼513室